Landing Page > Opt-in > Offer: This is usually the best method. You bring the visitor to your website or funnel system. You have a giveaway for email signup. The email signup starts an autoresponder sequence that provides more information, gains trust and closes the deal. Consider adding a bonus offer to set yourself apart from other affiliate marketers of the same product.
You'll also need ecommerce software, fulfillment software, worry about warehousing, customer service and refunds. But that's not all. You'll also need traffic. Think search engine optimization, Facebook ads, and other social media campaigns. It is hard work, especially on your own. You could opt for Amazon's platform, which might be the easier route. But, then again, at the end of the day, this is a serious business, which could produce significant profits. So you're either all in or you're not.
ClickBank represents primarily digital or downloadable products. These typically have high-percentage payouts to affiliates. The commissions average around 50%. You do need to be careful and closely vet all products. There are some great products, some good products, and many crap products. You need to be sure the product and the promotional methods are appropriate for your audience. But ..